Insure® ONE™

According to the CDC, colorectal cancer is the second leading cause of cancer-related deaths in the United States. It is the third most common cancer in men and women. (1)

InSure® ONE™ test can be used in screening programs for colorectal disease. InSure® ONE™ is a user-friendly, in-home collection test for blood in stool. Our brush technology has been proven to encourage more people to be screened. (2)


InSure® ONE™ is a fecal immunochemical test (FIT). It is a highly accurate test for detecting blood in stool, which may be an indication of lower gastrointestinal bleeding associated with disorders such as diverticulitis, ulcerative colitis, polyps, colorectal cancer or large adenomas that bleed.

The American Cancer Society (ACS) recommends both men and women at average risk for developing colorectal cancer (CRC) beginning screening at age 45. Read more here.

Risk Factors for Colorectal Cancer (3)

  • Men and women age 50 and older
  • Family history of colon cancer
  • History of colon or rectal polyps
  • Inflammatory bowel disease (Crohn’s or ulcerative colitis)
  • Familial adenomatous polyposis (FAP)
  • Hereditary non-polyposis colon cancer
  • Obesity
  • Smoking
  • Heavy alcohol use
  • Racial and ethnic background (African American & Ashkenazi Jewish)

Why Use InSure® ONE™

InSure® ONE™ is easy.

  • InSure® ONE™ is the only FIT that is performed using toilet water collected from a single bowel movement. (4)
  • You only need to gently brush the surface of the stool in water for about 5 seconds with the convenient, long-handled blue brush, and then simply collect the toilet water on the test card.  
  • No other FIT has this convenient, water-based collection method – if you have used a paintbrush, you can use InSure® ONE™. (4)
  • InSure® ONE™ test samples are collected in the privacy of your home, then submitted to your doctor’s office or laboratory for analysis.
  • There are no diet or medication restrictions associated with using InSure® ONE™.
  • ​The InSure® ONE™ test is available from your doctor. The Patient Collection Kit contains everything you need to collect at home and submit for analysis.



(2) A randomised trial of the impact of new faecal haemoglobin test technologies on population participation in screening for colorectal cancer. Cole et al. Journal of Medical Screening 2003