Publications
Journal articles
Graham L, Pedersen S, Brown G, Ho T, Kassir Z, Moynihan A, Vizgoft E, Pimlott L, Dunne R, Young G, LaPointe L, Molloy P. Colorectal Neoplasia Differentially Expressed (CRNDE), a Novel Gene with Elevated Expression in Colorectal Adenomas and Adenocarcinomas. Submitted for publication
LaPointe L, Pedersen S, Dunne R, Brown G, Pimlott L, Gaur S, McEvoy A, Thomas M, Wattchow D, Molloy P, Young G. Discovery and validation of molecular biomarkers for colorectal adenomas and cancer with application to blood testing. Submitted for publication
LaPointe L, Dunne R, Worthley D, Molloy P, Wattchow D, Young G. Map of differential gene expression in the normal colon. Physiological Genomics 33:50-64, 2008
Invited Talks and Key Presentations
“Genes to Products: Translating Tissue Discovered Biomarkers for Colon Cancer to Blood-Based Testing” LaPointe L.
CHI’s Early Oncology Partnering Forum, San Francisco, CA, USA, 2011
“Biomarkers of colorectal neoplasia: Strategies for successful translation from tissue discovery to blood- based testing” Pedersen S.
Biomarkers in Diagnostics & Therapeutics, Singapore, 2011
“Towards an early diagnosis and improved prognosis for CRC” LaPointe L.
CSIRO Preventative Health Flagship Annual Conference, Adelaide, SA, Australia, 2010
“Biomakers for Colorectal neoplasia” Pedersen S.
Institute of Molecular Cancer Research, University of Zurich, Switzerland, 2009
“From Genes to Products” LaPointe L.
CSIRO Executive Management Committee Science Day. Melbourne, VIC, Australia, 2008
“Discovering markers for colorectal neoplasia” LaPointe L.
CSIRO Preventative Health Flagship Annual Conference. Aitken Hill, VIC, Australia, 2007
“Brave New World: Advances in Genomics; Gene expression mapping in the normal colon” LaPointe L.
NZ Bio Conference, Auckland, New Zealand, 2007
“Adenoma Genomics Program” LaPointe L.
MD Anderson Cancer Center, Houston TX, USA, 2007
“The normal colon gene map: From maths to genes” LaPointe L.
Australian Gastroenterology Week, Adelaide SA, Australia, 2006
“Mapping gene expression along the normal colon” LaPointe L.
CSIRO Preventative Health Flagship Annual Conference. Aitken Hill, VIC, Australia, 2006
“Overview of the Adenoma Genomics Program” LaPointe L.
CSIRO Strategic Advisory Committee (Health). Melbourne, VIC, Australia, 2006
“Adenoma Genomics Program” LaPointe L.
CSIRO Preventative Health Flagship 'Deep Dive' Science Review (Ministerial Funding Review). Sydney, NSW, Australia, 2006
Conference Abstracts
Thomas M, Pedersen S, McEvoy A, Vizgoft E, Gaur S, Beeston I, LaPointe L. Plasma Testing of Gene Expression Biomarkers for Colorectal Neoplasia discovered in Neoplastic Colorectal Tissue. Digestive Disease Week (AGA), Chicago USA 2011
LaPointe L, Dunne R, Molloy P, Clark L, Ho T, Pedersen S, Young G. Biomarkers with high sensitivity and specificity for colorectal adenomas and carcinomas. Digestive Disease Week (AGA), Chicago USA 2009
Pedersen S, Brown G, Graham L, Dunne R, Molloy P, Clark L, Young G, LaPointe L. A novel colorectal neoplasia gene (CRNG) with high sensitivity and specificity for both adenomas and carcinomas. Digestive Disease Week (AGA), Chicago USA 2009
Pedersen S, Richards E, McEvoy A, Dunne R, Brown G, Clark L, Young G, LaPointe L. Alternative splicing of S100A11 in colorectal adenomas and carcinomas. Digestive Disease Week (AGA), Chicago USA 2009
Moynihan A, Molloy P, Papangelis V, Young G, LaPointe L. Upregulation of mesolthelin, RegIV, and transcobalamin in colon adenomas and cancer. Digestive Disease Week (AGA), Chicago USA 2009
LaPointe L, Ho T, Clark L, Dunne R, Molloy P, Young G. Identification of biomarkers for colorectal adenomas. Australian Health and Medical Research Congress: Australian Colorectal Cancer Group. Brisbane, Australia 2008
Moynihan A, Molloy P, Papangelis V, Young G, LaPointe L. Upregulation of IGBP2, Mesothelin and Transcobalamin I in colon adenomas and cancer. Australian Health and Medical Research Congress: Australian Colorectal Cancer Group. Brisbane, Australia 2008
LaPointe L, Dunne R. Normalization of custom microarrays. Australian Microarrays Conference (AMATA), Brisbane, Australia 2007
Wilson B, Phatak A, LaPointe L. Associative gene networks from microarray data in the normal colon. CSIRO Mathematical and Informational Sciences Annual Divisional Conference. Leura, NSW, Australia 2006
LaPointe L, Dunne R, Worthely D, Molloy P, Wattchow D, Young G. Mapping gene expression along the anterior-posterior axis of the adult human colon. Digestive Disease Week (AGA), Los Angeles, USA 2006
LaPointe L, Worthely D, Dunne R. Comparison of classification methodologies to discover biomarkers from gene expression data. Australian Microarrays Conference (AMATA). Barossa Valley, Australia 2005
Kiiveri H, Dunne R, LaPointe L. Canonical Variate Analysis and Microarrays. Australian Microarrays Conference (AMATA), Barossa, Australia 2005
LaPointe L, Dunne R. Comparison of machine learning techniques to identify biomarkers for colorectal cancer in publicly available data. International Society of Computational Biology, Detroit, Michigan, USA 2005
LaPointe L, Dunne R. Identification of colorectal cancer biomarkers using publicly available gene expression data. Digestive Disease Week (AGA), Chicago, USA 2005
LaPointe L, Young G, Chandler H. Analysis of mRNA expression profiles in colorectal adenomas using k-nearest neighbor cluster analysis. Digestive Disease Week (AGA), Orlando, USA 2003
